Catalyst Biosciences Announces Agreement to Sell Three NNR Assets to Attenua
-- Divestment of Certain Neuronal Nicotinic Receptor Assets to Provide Catalyst with
-- Catalyst Remains Focused on Core Therapeutic Areas, Especially Hemophilia --
Catalyst is focused on developing protease-based medicines in the fields of hemostasis and inflammation, and prior to its merger with Targacept, decided not to develop the NNR assets. The divestiture provides an upfront payment to Catalyst and may also allow Catalyst to receive up to a total of
Catalyst President and Chief Executive Officer,
NNR agonists are a class of central nervous system drugs targeting neuronal nicotinic receptors (NNRs), also known as neuronal acetylcholine nicotinic receptors (nAChRs), which modulate the flow of neurotransmission throughout the brain and nervous system. Under the terms of the agreement, Attenua will acquire certain oral NNR assets including related intellectual property rights and materials. The assets sold to Attenua include three molecules that have aggregate clinical experience in over 1200 patients with depression, ADHD and Alzheimer’s disease in Phase 1 and 2 clinical trials.
Attenua President and Chief Executive Officer,
Catalyst is a clinical-stage biopharmaceutical company focused on creating and developing novel medicines to address serious medical conditions. To date, Catalyst has focused its product development efforts in the field of hemostasis, including the treatment of hemophilia and surgical bleeding, and in the field of inflammation, including prevention of delayed graft function in renal transplants and the treatment of dry age-related macular degeneration, a condition that can cause visual impairment or blindness. Catalyst’s most advanced program is an improved next-generation coagulation Factor VIIa variant, CB 813d, which has successfully completed a Phase 1 clinical trial in severe hemophilia A and B patients. In addition to Catalyst’s lead Factor VIIa program, Catalyst has two other next-generation coagulation factors, a Factor IX variant, CB 2679d/ISU 304, that is in advanced preclinical development, and a Factor Xa variant, that is in the advanced lead stage of development. For more information, please visit www.catalystbiosciences.com.
Attenua is a clinical-stage biotech company focused primarily on developing novel, non-narcotic medicines to treat cough. Cough is a neglected medical problem in which no new drugs (NMEs/NCEs) have been approved since 1958. In
Catalyst Biosciences Forward-Looking Statements
This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statement of historical facts, included in this press release regarding the potential uses of the Company’s product candidates and the Company’s product development plans, are forward-looking statements. Examples of such statements include, but are not limited to, statements relating to potential milestone and royalty payments that Catalyst may receive from Attenua. Actual results or events could differ materially from the plans, intentions, expectations and projections disclosed in the forward-looking statements. Various important factors could cause actual results or events to differ materially from the forward-looking statements that Catalyst makes, including, but not limited to, the risk that Attenua will not be successful in the development or commercialization of the NNR products it is acquiring. Other risks and uncertainties related to Catalyst’s business are described in the “Risk Factors” section of the Company’s Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the
Catalyst Bioscience Contacts: Investors:
Fletcher Payne, CFO Catalyst Biosciences, Inc.650.871.0761 email@example.com Media: Denise Powell Red House Consulting, LLC510.703.9491 firstname.lastname@example.org Attenua, Inc.Contact: Jing Liang, CEO Attenua, Inc.212.203.8362 email@example.com